Top Senior Machine Learning Jobs in Los Angeles, CA

Build and improve large-scale machine learning models for aviation prediction products, including runway landing times, gate arrivals, and taxi durations. Develop high-performance systems using historical aviation data and complex data types, contribute ideas in an agile environment, and improve operational efficiency for airlines and airports. Preferred experience includes Kubernetes, AWS, GPU acceleration, graph neural networks, geospatial data, observability, ETL orchestration, and large-scale data processing.

Develop and deploy deep learning models for electro-optical and infrared image processing. Build ML pipelines for data ingestion, feature engineering, training, and inference; collaborate on computer vision solutions; prototype systems for operational integration; troubleshoot and maintain software; and evaluate emerging ML tools and techniques.

Own the full lifecycle of production classification and detection models, including transformer fine-tuning, entity detection, behavioral risk scoring, training, serving, versioning, evaluation, drift detection, and retraining. Build SageMaker-based ML systems and define output contracts supporting audit and policy enforcement. Lead the evaluation harness and mentor a co-op while operating as the company’s sole ML engineer.

Design, build, evaluate, and productionize machine learning and LLM-based agentic systems for healthcare products. Own projects end-to-end, including problem framing, dataset development, modeling, evaluation, deployment, monitoring, and safety guardrails. Build ML infrastructure, data pipelines, inference systems, and evaluation frameworks. Collaborate with clinicians, product managers, and engineers, while setting technical direction and mentoring team members.

Designs, deploys, and operates production machine learning systems for identity resolution, scoring, deliverability, and personalization. Responsibilities include feature engineering, model training, real-time inference, graph database integration, monitoring, drift detection, retraining, low-latency APIs, and scalable data processing. The role also contributes to MLOps standards, GPU acceleration, and ML architecture while partnering with platform engineering.

Lead the design, development, deployment, and operation of production-grade generative AI and LLM solutions. Build data and ML pipelines, fine-tune and evaluate models, implement RAG and prompt engineering, and establish MLOps practices on AWS. Drive use cases across insurance workflows, ensure security and responsible AI compliance, mentor engineers, and collaborate with product, engineering, security, finance, and go-to-market teams.

Develop autonomy evaluation metrics, statistical and machine-learning analyses, dashboards, and pipelines for simulation and on-road autonomous vehicle testing. Analyze perception, prediction, and planning performance; identify anomalous behavior and critical scenarios; apply VLMs and LLMs where appropriate; and support release gating and safety decisions. The role requires production Python, C++ debugging, technical leadership, cross-functional collaboration, and rigorous software engineering practices.

Develop and deploy machine learning models for fraud detection and credit risk decisioning. Own the full ML lifecycle, including data exploration, feature engineering, experimentation, validation, deployment, monitoring, and optimization. Analyze fraud trends and portfolio outcomes, collaborate with Product, Engineering, and Risk Operations, apply generative AI tools, and mentor fellow scientists while delivering measurable improvements in fraud prevention and responsible credit access.

Build and operate distributed GPU training platforms for foundation models. Run and debug multi-node PyTorch and Ray Train workloads, tune GPU networking and scheduling, profile performance, and develop benchmarks and evaluation harnesses. Partner with infrastructure teams and client scientists to improve throughput, reliability, cost efficiency, observability, and end-to-end training pipelines on GKE.

Own the strategy, design, implementation, and productionization of machine learning capabilities for an unpublished R&D game project. Build reusable training and evaluation pipelines, apply reinforcement learning to improve decision-making, establish research-to-production and reliability practices, guide experimentation, and strengthen engineering standards. Collaborate across engineering, design, data science, and analytics while mentoring engineers and addressing technical risks.

Lead the development and production deployment of applied machine learning and LLM solutions across product, marketing, and operations. Own ranking, recommendation, filtering, personalization, experimentation, and model evaluation systems. Partner with business and technical teams to identify valuable use cases, establish modeling best practices, and ensure reliable production deployment. Manage and mentor applied ML practitioners while maintaining technical rigor, business alignment, and measurable customer and revenue impact.

Lead the design, development, deployment, and operation of production AI and ML systems. Build high-throughput Python services and Databricks pipelines, support traditional ML and LLM applications, establish testing and deployment standards, and develop monitoring for quality, reliability, latency, throughput, and cost. Partner with product, research, and responsible AI teams on governance and release criteria. Provide architectural leadership, conduct code reviews, mentor engineers, and resolve complex technical dependencies.

Leads Tala’s Machine Learning Engineering team in building and operating platforms for model development, real-time inference, streaming features, batch processing, deployment, monitoring, and production reliability. Manages and develops 4–6 engineers, owns delivery and prioritization, provides architectural leadership, improves engineering practices and SLOs, and partners with Data Science, Data Engineering, Product, Credit, and Business Development teams.

Design, develop, and evaluate large-scale multimodal foundation models for biological research. Build hybrid LLM and graph neural network architectures, relational foundation models, and distributed multi-GPU training systems. Apply deep learning theory to biological data, transition research prototypes into scalable production systems, publish peer-reviewed research, and mentor junior staff while collaborating across scientific and engineering teams.

Build and deploy scalable AI and machine learning products for clinical research, including patient recruitment, enrollment forecasting, and study feasibility. Develop ML models, LLM-powered agents, data pipelines, and MLOps infrastructure using cloud services and CI/CD automation. Collaborate with cross-functional teams to integrate AI into clinical research workflows, monitor model performance, and advance reliable, unbiased solutions that improve patient outcomes.

Design and deploy production recommendation and retrieval engines, build data orchestration pipelines for multiple modalities, implement agentic workflow frameworks, and prototype, optimize, and scale models with monitoring, governance, and low-latency SLAs.

Leads and develops a perception and machine learning engineering team building computer vision, sensor fusion, tracking, detection, and scene-understanding capabilities for autonomous systems. Owns roadmap planning, technical decisions, delivery, model development and deployment workflows, field readiness, hiring, performance management, and cross-functional execution with autonomy, embedded, data, hardware, product, programs, and field operations teams.

Design, build, and maintain optimization technology, full-stack systems, and data-intensive scheduling infrastructure. Improve optimization algorithms using linear optimization, machine learning, and generative AI. Lead complex technical initiatives, establish testing and observability, support scalable operations, troubleshoot customer issues, participate in on-call rotations, and mentor engineers while partnering closely with product and engineering teams.

Build and scale production AI systems for Prophetic’s real estate intelligence platform. Responsibilities include developing agentic systems, data pipelines, inference workflows, evaluation benchmarks, geospatial processing, and machine learning applications across hundreds of millions of records. The role requires shipping reliable Python services, optimizing throughput and cost, integrating research into products, and collaborating with engineering and product teams.

Lead development and deployment of predictive and ML models for credit risk, collections, and operations. Mentor data scientists, promote MLOps and modern tools, present insights to stakeholders, and drive experimentation with techniques such as causal inference and GenAI.

Develop and deploy machine learning models and production software for multi-object tracking in autonomous trucks. Responsibilities include sensor fusion across camera, LiDAR, and radar; scalable PyTorch training workflows; tracking algorithm development; large-scale data analysis; C++ and Python engineering; safety and validation strategy; architecture decisions; and cross-functional collaboration. The role also provides technical leadership through design reviews, code reviews, mentoring, and engineering best practices.

Lead the development of machine learning systems for Cedar Pay's Personalization Engine, manage ML engineers, and ensure ML model effectiveness.

Build and operate production machine learning systems for Airbnb Payments, including LLM agents, real-time fraud detection, anomaly detection, personalization, and checkout optimization. Design, train, deploy, monitor, and continuously improve batch and streaming AI applications at global scale. Partner with product, engineering, operations, and data science teams, establish model governance and testing standards, and mentor engineers.

Lead design and productionalize ML algorithms and pipelines to detect account-sharing fraud in real time. Build scalable preprocessing, training, deployment, monitoring, and A/B testing solutions with cross-functional teams to optimize detection while minimizing user disruption.

Own the full machine learning lifecycle for search ranking and retrieval, including model training, deployment, serving, feature pipelines, evaluation frameworks, hybrid lexical-vector retrieval, large-scale embedding inference, query understanding, and permissions-aware multi-tenant search. Collaborate with infrastructure, AI, and backend teams to improve search relevance across ClickUp’s platform.