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Top Senior Python Jobs in Los Angeles, CA
Agency • Information Technology • Software • App development
Design, develop, and maintain scalable Python applications and cloud-native solutions. Architect microservices, containerized deployments (Docker/Kubernetes), optimize cloud infrastructure, build CI/CD pipelines, integrate messaging systems, ensure security and high code quality, and mentor junior developers. Generative AI/ML experience is a plus.
Top Skills:
AWSAzureAzure PipelinesCi/CdCosmosdbDjangoDockerFastapiFlaskGenerative AiGitlab CiGCPHugging FaceJenkinsKafkaKubernetesPythonPyTorchRabbitMQRdsRest ApisServerlessTensorFlowWebsockets
Artificial Intelligence • Information Technology • Professional Services • Software
The Senior Full Stack Developer will design, develop, test, and debug software solutions, collaborating with teams and optimizing applications. Responsibilities include user interaction design, back-end functionality, and ensuring software scalability and security.
Top Skills:
CSSDjangoDockerFastapiFlaskGitGnu/LinuxHTMLJavaScriptMongoDBMySQLNode.jsOraclePostgresPythonReactSvnVue
Logistics • Software • Transportation
The Principal Python Engineer will design, build, and maintain backend services and APIs, focusing on system reliability and engineering quality. The role involves working with databases, applying DevOps practices, and leveraging AI for development efficiency.
Top Skills:
DockerFastapiKubernetesPostgresPulumiPythonTemporalVue
Cloud • Software
The Python Engineer will write maintainable Python software, lead technical initiatives, collaborate globally, and contribute to community engagement at Canonical.
Top Skills:
CC++DockerGoKubernetesLinuxNoSQLPythonRustSQL
Software • Web3
The Senior Full Stack Engineer will lead the development of scalable backend services using Python and AWS Serverless, mentor team members, and integrate AI tools into the software development lifecycle.
Top Skills:
Ai ToolsAngularAWSCi/CdCloudFormationDynamoDBEventbridgeKinesisLambdaNode.jsPythonReactSagemakerSqsStep FunctionsTerraformVue
Artificial Intelligence • Consumer Web • Digital Media • Software
Design, implement, and scale event-driven, distributed backend systems in Python on AWS to process and enrich large-scale document and media datasets. Lead technical projects, mentor engineers, integrate ML/LLM components, optimize performance, maintain observability, and collaborate with Data Science, ML Engineering, and Product to deliver reliable high-throughput content processing services.
Top Skills:
AirflowAWSCloudwatchDatabricksDatadogEcsElasticacheLambdaLlmMachine LearningPythonScalaSnsSparkSqsTerraform
Artificial Intelligence • Consumer Web • Digital Media • Software
Design, build, and optimize event-driven, distributed backend systems and APIs in Python for large-scale content metadata extraction and enrichment. Deploy and operate resilient AWS-based pipelines, collaborate with ML teams to integrate models, and ensure system performance, observability, and data integrity.
Top Skills:
AirflowAws CloudwatchAws EcsAws ElasticacheAws LambdaAws SnsAws SqsDatabricksDatadogLlmMachine LearningPythonScalaSparkTerraform
Artificial Intelligence • Consumer Web • Digital Media • Software
Design, build, and scale event-driven, distributed backend systems in Python to extract and enrich metadata at massive scale. Lead architecture, mentor engineers, integrate ML/LLM components, optimize performance, and ensure observability and reliability across AWS-based pipelines.
Top Skills:
AirflowAws CloudwatchAws EcsAws ElasticacheAws LambdaAws SnsAws SqsDatabricksDatadogLlmMachine LearningPythonScalaSparkTerraform
Big Data • Cloud • Software • Database
The Senior Python Engineer will develop and support MongoDB Python drivers, enhance library quality, and collaborate on product features.
Top Skills:
Ai/Ml FrameworksMongoDBPypiPython
Travel
As a Staff Software Engineer, you’ll lead the design and reliability of Duetto's data lakehouse, evolving data systems using Python and AWS, ensuring data quality, and implementing AI-driven solutions.
Top Skills:
AirflowAWSDatadogDockerGithub ActionsGlueIcebergPysparkPythonSagemakerSentrySumo LogicTerraform
Artificial Intelligence • Information Technology • Machine Learning • Marketing Tech • Software • Biotech • Design
Develop and maintain backend solutions, ensuring performance, security, and regulatory compliance, while collaborating in cross-functional teams.
Top Skills:
AWSFastapiPython
Information Technology • Consulting
Design and build applications using Python, manage component design, optimize performance, and collaborate with clients on innovative products.
Top Skills:
Ai ToolsCi/CdGitGoKubernetesPythonReact
New
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Legal Tech • Software
Design and implement durable, fault-tolerant AI orchestration and backend systems using Temporal and agentic ReAct patterns. Deliver features end-to-end with testing, CI/CD, monitoring, and observability; mentor engineers and collaborate with cross-functional teams to translate legal workflows into reliable AI-powered features.
Top Skills:
Async/AwaitClaude (Llm)Event-Driven ArchitectureFastapiGitlab Ci/CdMessage QueuesNew Relic ApmOctopus DeployPlaywrightPydantic V2Pydantic-AiPytestPython 3.12+ReactStructlogSyrupyTemporal
HR Tech • Legal Tech • Software • Consulting
Design, implement, and maintain SaaS features using Python and React on AWS. Lead system design, code reviews, CI/CD pipelines, AI-integrated development (LLMs and AI coding agents), prompt engineering, testing (Cypress), and on-call production support. Mentor teammates and ensure secure, scalable, well-documented software.
Top Skills:
AWSCicdClaude CodeCodexContainerized EnvironmentsCypressDevin.AiLlmMcpMySQLPython 3.11ReactRestful Apis
Machine Learning • Other
The Backend Software Engineer will develop and maintain backend systems for data processing related to coffee farming, utilizing Python and PostgreSQL. Responsibilities include feature development, problem-solving, and adapting systems to regulatory changes while ensuring system resilience.
Top Skills:
AWSCi/CdDockerPostgresPostgresql/PostgisPythonTerraform
Healthtech • Software
Lead backend development on the scheduling platform modernization, contribute across products, write APIs, and drive AI-accelerated software development workflows.
Top Skills:
.NetAgent OrchestrationAi-Assisted DevelopmentLlm ToolingPython
Healthtech • Software
Lead backend development on the scheduling platform modernization. Contribute across Python and .NET ecosystems, write APIs, review code, and support AI-accelerated development workflows while collaborating in a remote team environment.
Top Skills:
.NetAi-Assisted Development WorkflowsClaude CodeLlm ToolingMulti-Agent SystemsPython
10 Days AgoSaved
Travel
Lead development of Python-based web applications using Django and FastAPI, architect scalable solutions, and establish technical standards while mentoring developers and optimizing infrastructure.
Top Skills:
Ai Coding AssistantsAWSDjangoFastapiGitPostgresPythonRailway
Reposted 12 Days AgoSaved
Artificial Intelligence • Food • Software
The Senior Full Stack Engineer will develop scalable web applications using Python and React.js, mentor team members, and enhance system performance while leveraging AI technologies. The role emphasizes collaboration, end-to-end feature ownership, and architectural improvements in a remote setting.
Top Skills:
AWSCi/CdClaude CodeCodexDatadogDockerGithub ActionsGraphQLMySQLNew RelicPostgresPythonReactRestful ApisSentrySQL
Information Technology • Consulting
Lead the development of data science dashboards to mitigate fire hazards, collaborating with various teams to enhance the web application and optimize backend services.
Top Skills:
AWSFlaskJavaScriptPythonRestful Api
Artificial Intelligence • eCommerce • Software
Design and build backend systems and APIs for AI-driven products, ensuring scalability, reliability, and integration of ML models while collaborating with engineering and product teams.
Top Skills:
APIsAWSAzureDockerGCPKubernetesLlmsMachine LearningNoSQLPythonSQL
Digital Media
Develop and enhance features for EnrollWise, contribute to a scalable software architecture, review code, collaborate on design and technical feasibility, and maintain software quality.
Top Skills:
ApolloAWSDjangoDjango OrmGraphQLNextjsPythonReact
Digital Media • Professional Services • Consulting • Financial Services
The Senior Python Developer will enhance commerce and communication infrastructure by developing features, collaborating with stakeholders, ensuring system reliability, and integrating with third-party tools, while maintaining high-performance standards.
Top Skills:
Ci/CdDockerFastapiPostgresPythonRabbitMQRedisStripe
Database • Analytics
As a Senior Software Engineer, you'll enhance ClickHouse's Python integrations, drive AI integration strategies, and collaborate with open-source communities, requiring deep expertise in data engineering and AI applications.
Top Skills:
Apache AirflowDagsterDbtLangchainLlamaindexN8NNumpyPandasPrefectPydanticPython
Artificial Intelligence • HR Tech • Information Technology • Software
As a Founding Staff Software Engineer, you will lead the design and development of robust backend systems and APIs, optimize large-scale data workflows, and mentor a growing engineering team.
Top Skills:
AWSCeleryFastapiOpensearchPostgresPythonRedisTemporal
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