Top Senior IT Jobs in Los Angeles, CA

Lead and develop an IT team to run secure, scalable infrastructure and support services. Oversee daily operations, project delivery, vendor management, compliance with security/regulatory frameworks, performance metrics, budgeting, and continuous improvement while partnering with business leaders.

Lead corporate IT strategy and operations for a remote, cloud-first company. Manage a five-person remote IT team and contractors, operate helpdesk, oversee endpoints, identity, MDM, EDR, patching, networks, inventory and ticketing systems, manage IT budget and vendors, and partner with InfoSec on PCI DSS compliance.

Lead and govern global IT change management lifecycle: intake, risk-based assessment, approvals, execution, validation, post-change review, reporting, and continuous improvement. Coordinate across IT teams, vendors, MSPs, and regions to minimize service disruption, maintain audit-ready records, deliver training, and drive tooling and process automation opportunities to support high-availability and data center operations.

Administer and secure enterprise IT and OT environments across sites, supporting Windows Server, virtualization, networking, cloud (Azure/M365), PLC/SCADA integrations, backups, DR, segmentation and Zero Trust initiatives. Provide Tier 2/3 escalation, network/OT troubleshooting, monitoring, documentation, compliance support, and collaborate with infrastructure, security, and manufacturing teams to maintain production uptime.

Lead IT operations and strategy for enterprise systems, cloud infrastructure, networks, servers, and business applications. Ensure 24/7 production support, implement monitoring and security, manage maintenance/patching/backups, document inventories and processes, coordinate cross-site support, recommend technology improvements, and recruit/lead IT staff while prioritizing and delivering multiple projects.

Lead global IT operations for a HIPAA-regulated healthtech company, managing a small support team and hands-on ticketing. Build and maintain systems for compliance and visibility, optimize vendor costs, implement security/onboarding processes, drive process improvements with KPIs and automation, and serve as primary IT liaison to leadership and partners.

Provide frontline and advanced application support for radiology imaging workflows: incident triage, user provisioning, configuration changes, DICOM troubleshooting, monitoring interfaces, coordinating with networks/storage/vendors, maintaining SOPs and knowledge base, delivering end‑user training and on‑call doctor support to meet SLAs.

Manage and grow a remote helpdesk team while providing hands-on tier 2/3 support. Own ticket triage, SLAs/KPIs, onboarding/offboarding, M365/Google Workspace and Azure AD administration, endpoint management via Intune/MDM, vendor and asset lifecycle, security policy enforcement, documentation, and process improvement.

Build and lead a centralized IT function across a holding company and portfolio. Run acquisition IT workstreams and create a Day 1-100 integration playbook. Select and operate identity and access systems, build joiner/mover/leaver processes, maintain living inventory of tools/accounts/licenses, manage MSP relationships and vendor contracts, and connect back-end systems to the cross-portfolio data platform while engaging business stakeholders.