Twist Bioscience Logo

Twist Bioscience

Sr Technical Product Owner

Posted 4 Days Ago
Be an Early Applicant
In-Office
South San Francisco, CA
160K-191K Annually
Senior level
In-Office
South San Francisco, CA
160K-191K Annually
Senior level
Own functional requirements and solution definition for cross-system initiatives spanning product, engineering, commercial, scientific, and operational teams. Translate business needs into epics, user stories, acceptance criteria, and business rules; lead stakeholder alignment, grooming, end-to-end user acceptance testing, launch support, and stabilization. Partner with engineering, architecture, project management, and quality teams while ensuring audit readiness, customer focus, and continuous improvement.
The summary above was generated by AI
Sr Technical Product Owner (Hybrid in South San Francisco, CA) About the Role

At Twist Bioscience, we're scaling the digital systems that power our synthetic DNA platform
and enable innovation across our commercial, scientific, and operational teams. We're seeking
a Senior Technical Product Owner to lead cross-functional system projects, someone who can
dive deep into the details while helping improve how we work.
In this role, you will own hands-on work across requirements gathering, documentation, and
testing for high-impact system initiatives. We are looking for someone with a proven track record
of maintaining effective business relationships to ensure IBT can deliver solutions that align with
business strategies and objectives. This role sits at the intersection of product, engineering,
and business.
The ideal candidate has a strong analytical mindset, solid experience with enterprise and
technical systems, and a knack for translating complex business and product needs into clear,
executable technical requirements.

What You will do                                                                                                                                                                                                                     

You will serve as the primary business-facing partner on system initiatives, owning the functional definition of what needs to be built and partnering closely with engineering and project management, who own technical design, delivery sequencing, and timelines.

Requirements and Solution definition

● Lead requirements intake and clarification with business stakeholders across functions
(e.g., Product, Marketing, Sales Operations, Finance, Customer Support, and R&D).
● Define and document functional requirements, business rules, edge cases, and
acceptance criteria, including impacted existing logic, constraints, and exceptions, and
translate them into epics and user stories ready for development and QA.
● Identify impacted process areas, systems, and dependencies end to end (e.g., product
setup, pricing, quoting, order intake, manufacturing, fulfillment, and invoicing), along with
the SMEs and stakeholders within each.
● Drive alignment with cross-system partners and SMEs to ensure requirements are
complete and consistent across integrated systems and address emerging business
needs, positioning the organization to stay ahead of new commercial requests.
● Ensure requirements and solutions are compliant and audit-ready (e.g., SOX, ISO),
partnering with Finance, Quality and other internal stakeholders.
● Demonstrate strong customer empathy and advocate for customer needs throughout the
product development process

Delivery partnership and communication

● Provide development leads, architects, and project managers with the full end-to-end
context and scope of each initiative, and lead functional grooming sessions.
● Partner with project management, scrum masters, developers, architecture, and SWQA
through design, build, testing, and delivery, clarifying requirements and surfacing risks,
gaps, and dependencies early.
● Communicate proactively and consistently with business stakeholders on scope, status,
risks, and dependencies throughout each initiative.
● Influence scope tradeoffs and solution options by bringing business and cross-system
context to technical discussions.

Testing, launch, and stabilization

● Plan and lead end-to-end user acceptance testing across multiple systems: kick off with
testers, provide context and demos, support issue logging and defect clarification, and
obtain stakeholder sign-off before go-live.
● Support release, hypercare, and post-launch stabilization, providing business context to
help assess the criticality of issues.
● Stay informed on production issues and contribute business and system context to their
resolution.

Continuous improvement

● Share feedback and ideas to continuously improve how the team runs projects, gathers
requirements, and tests, including intake playbooks, documentation standards, and
testing practices.
● Look for opportunities to leverage AI tools to work more efficiently, such as in
requirements documentation, analysis, and testing.

Qualifications

● Bachelor's degree in a technical, engineering, or scientific field; minimum of 5+ years of
experience in a related field
● 5+ years of experience in technical product management, customer relationship
management, or products, systems, or applications experience.
● Ability to translate scientific, operational, or customer needs into functional specifications
that align with technical constraints and business goals.
● Excellent communication and collaboration skills, comfortable partnering with both
business stakeholders and technical teams.
● Growth mindset, with a drive to continuously improve systems and processes.
● Customer-centric mindset and strong sense of customer empathy
● Ability to work in a fast-paced, agile development environment
Preferred Qualifications
● Advanced degree (Master’s or PhD)
● Experience in biotech, life sciences, or synthetic biology environments.
● Hands-on experience with Salesforce (SFDC), such as Sales Cloud, Service Cloud, or
related integrations.
● Experience with Laboratory Information Management Systems (LIMS), including sample
tracking, workflow configuration, or integration with lab and enterprise systems.

About Twist Bioscience

Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.

At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.

The base cash compensation for this California-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations.
San Francisco Bay Area Pay Range
$160,000—$191,000 USD

Similar Jobs

28 Days Ago
In-Office
131K-150K Annually
Senior level
131K-150K Annually
Senior level
Fintech
Leads strategic planning and execution for complex enterprise platforms and products. Owns multiple product backlogs, translates business needs into technical requirements, aligns senior stakeholders, advocates for customers, and drives measurable outcomes. Mentors Technical Product Owners, leads cross-functional collaboration, supports user experience and journey discussions, tracks major product releases, and ensures solutions account for credit union regulatory and compliance requirements.
Top Skills: Agile Methodologies
One Month Ago
In-Office
Irvine, CA, USA
140K-160K Annually
Senior level
140K-160K Annually
Senior level
Big Data • Machine Learning • Software • Analytics
Own the marketing technology product roadmap and systems backlog while managing end-to-end delivery of Salesforce and marketing SaaS initiatives. Translate marketing goals into requirements, user stories, and technical priorities; coordinate developers, architects, BSAs, and stakeholders; facilitate Agile ceremonies and UAT; manage dependencies, risks, integrations, data flows, and deployment readiness; and communicate roadmap progress and technical tradeoffs to leadership.
Top Skills: APIsConfluenceHubspotJIRAKanbanMarketoPardotSaaSSalesforceScrum
2 Months Ago
In-Office
2 Locations
90K-115K Annually
Senior level
90K-115K Annually
Senior level
Fintech
Lead product ownership for Core Services platform, owning backlog, writing engineer-ready epics and user stories, prioritizing technical debt and regulatory risk, partnering with engineering/architecture/QA, enforcing release governance, monitoring production health, driving cross-team alignment, and providing executive reporting on roadmap, risks, and delivery outcomes.
Top Skills: Api VersioningCachingDistributed SystemsErdEvent-Driven DesignGraphQLMicroservicesRest

What you need to know about the Los Angeles Tech Scene

Los Angeles is a global leader in entertainment, so it’s no surprise that many of the biggest players in streaming, digital media and game development call the city home. But the city boasts plenty of non-entertainment innovation as well, with tech companies spanning verticals like AI, fintech, e-commerce and biotech. With major universities like Caltech, UCLA, USC and the nearby UC Irvine, the city has a steady supply of top-flight tech and engineering talent — not counting the graduates flocking to Los Angeles from across the world to enjoy its beaches, culture and year-round temperate climate.

Key Facts About Los Angeles Tech

  • Number of Tech Workers: 375,800; 5.5% of overall workforce (2024 CompTIA survey)
  • Major Tech Employers: Snap, Netflix, SpaceX, Disney, Google
  • Key Industries: Artificial intelligence, adtech, media, software, game development
  • Funding Landscape: $11.6 billion in venture capital funding in 2024 (Pitchbook)
  • Notable Investors: Strong Ventures, Fifth Wall, Upfront Ventures, Mucker Capital, Kittyhawk Ventures
  • Research Centers and Universities: California Institute of Technology, UCLA, University of Southern California, UC Irvine, Pepperdine, California Institute for Immunology and Immunotherapy, Center for Quantum Science and Engineering

Sign up now Access later

Create Free Account

Please log in or sign up to report this job.

Create Free Account