Genentech Logo

Genentech

Scientist 3, Immunology

Posted 11 Days Ago
Be an Early Applicant
In-Office
South San Francisco, CA
103K-192K Annually
Entry level
In-Office
South San Francisco, CA
103K-192K Annually
Entry level
Lead research projects investigating T-cell biology and immunoregulatory mechanisms, identify and validate therapeutic targets for inflammatory diseases, generate proof-of-concept data, design complex cellular and animal experiments, and collaborate across genetics, biomarker discovery, and early clinical development teams.
The summary above was generated by AI

The Hanna Lab in the Department of Immunology at Genentech is seeking a highly talented, driven and motivated Scientist 3 to investigate novel biological mechanisms and potential therapeutic targets to treat inflammatory diseases. The successful candidate will lead projects that advance our understanding of the cellular and molecular mechanisms of T cell biology, with a main emphasis on harnessing immunoregulatory mechanisms for reestablishing immune and tissue homeostasis under inflammatory conditions.

The Opportunity

  • Lead innovative research projects focused on understanding cellular and molecular mechanisms of T cell biology and immunoregulatory pathways.

  • Drive pipeline programs from discovery toward early clinical development by generating robust proof-of-concept data.

  • Design and execute experiments using state-of-the-art technologies, including primary cell isolation, multi-dimensional flow cytometry, and complex disease models.

  • Explore novel biological pathways to identify and validate new therapeutic targets for inflammatory diseases.

  • Collaborate cross-functionally with team members across human genetics, biomarker discovery, and early clinical development.

  • Present research findings regularly at intra- and inter-departmental meetings, fostering an open and inquisitive scientific culture.

Who You Are

  • You hold a PhD in Immunology, Molecular Biology, Biochemistry, or a related field with a strong track record of research achievement  in the form of high-quality publications

  • You possess hands-on expertise in cellular and molecular immunology techniques, including primary cell isolation, multi-dimensional flow cytometry, in vitro immunological assays, and in vivo animal models.

  • You have experience independently designing, executing, and interpreting complex scientific experiments.

  • You bring strong communication and collaborative skills, thriving in an open, team-oriented laboratory environment.

  • You are curious, open-minded, and passionate about advancing science to uncover novel biological mechanisms.

Preferred

  • Experience  in T cell biology and/or mucosal immunology.

  • Experience with analysis of data from genomic sequencing, scRNA-seq, TCR-seq, CITE-seq or spatial transcriptomics is preferred.

  • Experience in culturing 2D and 3D murine or human organoids or other complex in vitro systems is a plus.

 

Together, we’ll advance along the whole patient journey with the aspiration to prevent, stop and cure diseases.

Relocation can be offered for this position

The expected salary range for this position based on the primary location of California is $103,400 - $192,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  A discretionary annual bonus may be available based on individual and Company performance.  This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

Similar Jobs

18 Days Ago
In-Office
103K-192K Annually
Entry level
103K-192K Annually
Entry level
Healthtech • Biotech
Investigate cellular and molecular mechanisms of adaptive and innate immunity to identify therapeutic targets for inflammatory diseases. Lead preclinical research projects, design and interpret in vitro and in vivo experiments, generate proof-of-concept data, characterize mechanisms of action, and advance programs toward early clinical development. Collaborate across immunology, regenerative medicine, genetics, biomarker discovery, and clinical development teams while presenting research findings.
Top Skills: Cell EngineeringCite-SeqGenomic SequencingIn Vitro Immunological AssaysIn Vivo Animal ModelsMultidimensional Flow CytometryPrecision Genome EditingPrimary Cell IsolationScrna-SeqSpatial TranscriptomicsTcr-Seq
An Hour Ago
In-Office
106K-177K Annually
Entry level
106K-177K Annually
Entry level
Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Biotech • Pharmaceutical
Leads clinical pharmacology activities for a late-stage immuno-oncology program. Designs dose-finding strategies, analyzes pharmacokinetic data, supports clinical trial design and reporting, and drafts clinical pharmacology content for protocols, development plans, and regulatory documents. Collaborates with clinicians, statisticians, translational oncology, and clinical operations teams while providing scientific guidance and mentoring colleagues.
Top Skills: NonmemRSASWinbugs
7 Hours Ago
Remote or Hybrid
United States
60K-81K Annually
Mid level
60K-81K Annually
Mid level
Cloud • Fintech • Software • Business Intelligence • Consulting • Financial Services
Partner with skilled nursing and long-term care clients to assess and improve revenue cycle operations—admissions, payer authorization, MDS/PDPM reimbursement, billing, collections, and denials. Lead client engagements, recommend process and system improvements using EHR and billing data, manage project execution, deliver training, and support change management to optimize reimbursement and financial performance.
Top Skills: Billing SystemsElectronic Health Record (Ehr)Revenue Cycle Management Systems

What you need to know about the Los Angeles Tech Scene

Los Angeles is a global leader in entertainment, so it’s no surprise that many of the biggest players in streaming, digital media and game development call the city home. But the city boasts plenty of non-entertainment innovation as well, with tech companies spanning verticals like AI, fintech, e-commerce and biotech. With major universities like Caltech, UCLA, USC and the nearby UC Irvine, the city has a steady supply of top-flight tech and engineering talent — not counting the graduates flocking to Los Angeles from across the world to enjoy its beaches, culture and year-round temperate climate.

Key Facts About Los Angeles Tech

  • Number of Tech Workers: 375,800; 5.5% of overall workforce (2024 CompTIA survey)
  • Major Tech Employers: Snap, Netflix, SpaceX, Disney, Google
  • Key Industries: Artificial intelligence, adtech, media, software, game development
  • Funding Landscape: $11.6 billion in venture capital funding in 2024 (Pitchbook)
  • Notable Investors: Strong Ventures, Fifth Wall, Upfront Ventures, Mucker Capital, Kittyhawk Ventures
  • Research Centers and Universities: California Institute of Technology, UCLA, University of Southern California, UC Irvine, Pepperdine, California Institute for Immunology and Immunotherapy, Center for Quantum Science and Engineering

Sign up now Access later

Create Free Account

Please log in or sign up to report this job.

Create Free Account