The Head of Program Management leads program management functions, overseeing R&D, corporate programs, and portfolio management, while ensuring alignment with strategic goals.
About Us
Dianthus Therapeutics is a publicly traded, clinical-stage biotechnology company dedicated to designing and delivering novel, best-in-class monoclonal antibodies with improved selectivity and potency. Based in New York City and Waltham, Mass., Dianthus is comprised of an experienced team of biotech and pharma executives who are leading the development of next-generation antibody complement therapeutics, aiming to deliver transformative medicines for people living with severe autoimmune and inflammatory diseases. To learn more, please visit www.dianthustx.com and follow us on LinkedIn.
About the Role
As the Head of Program Management, you will be responsible for establishing and leading a centralized program management function across the organization.
Reporting to the Chief Development and Medical Affairs Officer, you will oversee the planning, execution, and delivery of all R&D and corporate programs, ensuring alignment with strategic goals, timelines, and budgets. The ideal candidate is a seasoned biotech leader with deep experience in program and portfolio management, cross-functional leadership, and organizational integration.
This is an exciting time to join a growing biotech company as we build a pipeline. We are building a culture of individuals who hold our core principles at the center of our operations, with the goal to elevate the care of our patients’ lives. We are open to you working remotely.
Key Responsibilities
- Build and Lead PMO: Design and implement a centralized Program Management Office to support all development programs and corporate initiatives.
- Program Oversight: Provide strategic oversight and hands-on leadership for key programs across discovery, preclinical, clinical, regulatory, and commercial functions.
- Integration & Alignment: Integrate existing program management practices across departments into a unified framework with standardized tools, processes, and governance.
- Portfolio Management: Develop and maintain portfolio dashboards, KPIs, and reporting mechanisms for executive leadership and board-level visibility.
- Cross-Functional Leadership: Partner with R&D, Clinical, Regulatory, Finance, and Operations to ensure program milestones are met and risks are proactively managed.
- Strategic Planning: Support long-range planning and scenario modeling to inform investment decisions and resource allocation.
- Team Development: Recruit, mentor, and develop a high-performing program management team.
Experience
- 15+ years of experience in biotech/pharma, with at least 7 years in program or portfolio management leadership roles.
- Advanced Degree highly preferred (PhD, MBA, or MS in Business or Scientific discipline).
- Proven track record of building and scaling PMO functions in high-growth environments.
- Deep understanding of drug development lifecycle from discovery through commercialization.
- Strong leadership, communication, and stakeholder management skills.
- Experience with project management tools and systems (e.g., Smartsheet, MS Project)
Top Skills
Ms Project
Smartsheet
Similar Jobs
Software
The Head of Marketing Program Management will lead and develop processes for marketing operations, manage a team, and ensure alignment across various marketing initiatives and campaigns.
Top Skills:
Asana
Cloud • Information Technology • Productivity • Security • Software • App development • Automation
Lead and develop the Technical Program Management organization, drive strategy, execution, and delivery of complex technical programs across the company.
Top Skills:
APIsArchitecturesModern Systems
Fintech • Social Impact • Software
Lead the Security & Risk department, overseeing cybersecurity and fraud prevention while implementing security automation and tools for innovation. Manage a skilled team, foster partnerships, and ensure physical security for employees and operations.
Top Skills:
AWSCloud SecurityDevsecopsKubernetesMachine LearningReal-Time Analysis
What you need to know about the Los Angeles Tech Scene
Los Angeles is a global leader in entertainment, so it’s no surprise that many of the biggest players in streaming, digital media and game development call the city home. But the city boasts plenty of non-entertainment innovation as well, with tech companies spanning verticals like AI, fintech, e-commerce and biotech. With major universities like Caltech, UCLA, USC and the nearby UC Irvine, the city has a steady supply of top-flight tech and engineering talent — not counting the graduates flocking to Los Angeles from across the world to enjoy its beaches, culture and year-round temperate climate.
Key Facts About Los Angeles Tech
- Number of Tech Workers: 375,800; 5.5% of overall workforce (2024 CompTIA survey)
- Major Tech Employers: Snap, Netflix, SpaceX, Disney, Google
- Key Industries: Artificial intelligence, adtech, media, software, game development
- Funding Landscape: $11.6 billion in venture capital funding in 2024 (Pitchbook)
- Notable Investors: Strong Ventures, Fifth Wall, Upfront Ventures, Mucker Capital, Kittyhawk Ventures
- Research Centers and Universities: California Institute of Technology, UCLA, University of Southern California, UC Irvine, Pepperdine, California Institute for Immunology and Immunotherapy, Center for Quantum Science and Engineering
