Software QA Engineer II

CRIO (Clinical Research IO) is a health tech company helping pharma, biotech, research sites, and academic research centers streamline regulatory workflows with one system and a single source of clinical data capture. Our modules allow sites to capture data electronically in real-time, providing data managers and monitors with enhanced transparency, and enabling remote monitoring by sponsors and CROs.

CRIO’s eSource and CTMS system is a leading, modern, enterprise platform built for clinical research sites. Since CRIO’s launch in 2016, CRIO has established the leading brand position in eSource and has won close to 50% of the emerging class of enterprise-grade site networks, many of whom are backed by institutional investors such as VC, PE and corporations. CRIO has achieved the attached metrics, all with little to no serious outbound sales or marketing.

We are seeking a detail-oriented and quality-driven Software QA Engineer II to join our growing Quality Assurance team.  The ideal candidate is a proactive and analytical tester with strong manual testing expertise and a passion for delivering high-quality software in a regulated healthcare environment. This role emphasizes deep functional validation, exploratory testing, and end-to-end quality ownership. You will play a critical role in designing and executing comprehensive test strategies, identifying edge cases, and ensuring product reliability across the software development lifecycle.  The ideal candidate also thrives in an Agile environment, collaborates closely with cross-functional teams, and takes full ownership of validating complex workflows from a user and business perspective.

Responsibilities

• Test Strategy and Planning: Develop, maintain, and execute detailed test plans, test cases, and test scenarios with a strong focus on manual validation of complex features and workflows.
• Functional and End-to-End Testing: Perform thorough manual testing, including functional, integration, and end-to-end validation across all stages of the SDLC (Dev, QA, UAT, Production).
• Exploratory Testing: Conduct in-depth exploratory testing to uncover edge cases, usability issues, and gaps not covered by predefined test cases.
• Regression Testing: Own and execute manual regression test suites to ensure stability of existing functionality, with a focus on high-risk and business-critical areas.
• Backend and Database Validation: Possess knowledge to navigate data and backend processes using SQL queries, ensuring accurate data flow and system behavior.
• API Testing: Perform manual API testing using tools such as Postman to validate request/response structures, error handling, and data consistency.
• Defect Management: Identify, document, and track defects with clear, detailed reproduction steps, severity/priority assessments, and expected vs. actual outcomes. Collaborate with developers to drive timely resolution.
• Cross-Functional Collaboration: Work closely with Product, Engineering, and other stakeholders to clarify requirements, refine acceptance criteria, and ensure test coverage aligns with business needs.
• Release Validation: Support release activities by executing pre-release, and post-deployment validation testing to ensure production readiness.
• Process Improvement: Identify opportunities to enhance manual testing practices, test coverage, and QA processes. Contribute to documentation and mentor junior QA team members on testing techniques and best practices.
• Compliance and Regulatory Awareness: Ensure all testing activities and documentation align with regulatory requirements, including data integrity, audit trails, and validation standards in clinical research software.

Skills/Experience

• 3–5 years of experience in software quality assurance with a strong emphasis on manual testing
• Deep understanding of QA methodologies, SDLC, and manual testing best practices
• Proven experience designing and executing detailed manual test cases and exploratory testing strategies
• Hands-on experience with test management tools and defect tracking systems (e.g., Jira)
• Strong SQL skills for backend and database validation
• Experience with API testing tools such as Postman or similar
• Familiarity with test automation concepts and collaboration with automation engineers (hands-on automation is a plus but not required)
• Experience working in Agile/Scrum environments and participating in sprint ceremonies
• Strong analytical thinking and problem-solving skills with exceptional attention to detail
• Excellent written and verbal communication skills, with the ability to clearly articulate defects, risks, and test results to both technical and non-technical audiences
• Bachelor’s degree or equivalent experience in computer science, engineering, information technology, or a related field

Nice to Have

• Experience testing SaaS applications in healthcare, life sciences, or clinical research environments
• Familiarity with regulatory requirements such as 21 CFR Part 11, HIPAA, CDISC ODM, HL7 FHIR, and GDPR
• Experience with usability testing and user workflow validation
• Exposure to automation frameworks (e.g., Selenium, Cypress, Playwright) and understanding of how manual and automated testing complement each other
• Understanding of eClinical systems, EDC platforms, and clinical data workflows
• Experience working with CI/CD pipelines and release processes

 Benefits & Perks:

• Work from anywhere
• Unlimited PTO
• 401k company match
• Healthcare
• Dental
• Vision (Company Paid 100%)
• Life insurance
• Professional Development Reimbursement
• Work From Home Expense Reimbursement

Salary Range: $75,000 --> $85,000

Equal Employment Opportunity:

CRIO is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. All employment decisions are made based on qualifications, merit, and business need without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran status, disability status, age, or any other basis protected by federal, state, or local law.

Disability Accommodation Statement:

We are committed to providing reasonable accommodations to individuals with disabilities in the application and interview process. If you require accommodation to participate in the application process, please contact Human Resources to request assistance.