Build and maintain high-performance TypeScript backend services and event-driven infrastructure. Design scalable APIs, integrate PostgreSQL/MySQL, AWS SQS, and Centrifugo, ensure reliability, security, and observability, optimize production systems, modernize legacy code, and own end-to-end feature delivery with strong testing, debugging, and performance tuning.
Sequencing is building the interface between humanity and its DNA.
Using clinical-grade whole genome sequencing, AI, and a rapidly expanding ecosystem of genomic applications, we help people better understand themselves, their health, and their future through their DNA.
The human genome is one of the most valuable and underutilized resources in the world. Our mission is to transform the human genome into a lifelong source of personalized guidance and build the trusted home for every genome on Earth.
As the world’s largest direct-to-consumer whole genome sequencing platform, Sequencing is helping define the future of AI-powered personalized health.
We’re a profitable, venture-backed, fully remote company building category-defining products that help people better understand themselves through their DNA.
As a Senior Backend TypeScript Engineer you build and maintain the high performance backend services that power our core personalized health experiences. You work side by side with other senior engineers to build and grow scalable infrastructure APIs and event driven services. When you do this well people get fast reliable personalized health insights from their genome instead of slow or broken experiences.
The Impact
- Design build and maintain performant backend services in TypeScript that power our core personalized experiences.
- Build and grow scalable infrastructure APIs and event driven services that deliver data driven features to users.
- Support and optimize production ready backend systems so they stay fast and dependable under load.
- Integrate and manage services such as PostgreSQL MySQL AWS SQS and Centrifugo in the backend.
- Make systems reliable secure and observable so people can trust their DNA data is safe.
- Own and drive end to end feature development with a strong eye on user experience.
- Write clean reliable code with performance and maintainability in mind from the start.
- Champion clean code technical excellence and continuous improvement across the team.
- Debug test and performance tune across services to catch problems before users feel them.
- Maintain modernize and migrate legacy code so older systems keep up with new demand.
- Take ownership of complex problems and drive them to a clear working solution.
Dominant and Expressed Traits
- 5+ years of backend development experience.
- Expert with TypeScript and comfortable owning production backend services.
- Experience with functional programming.
- Deep hands on experience with PostgreSQL MySQL and service based architectures.
- Strong debugging testing and performance tuning skills.
- Able to work independently while collaborating closely with key teammates.
- Customer driven with a passion for building systems that deliver exceptional experiences.
- Nice to have familiarity with genomics health data or personalization systems startup or fast paced environments or Rust.
- Comprehensive medical, dental, and vision insurance coverage
- 401(k) with company matching
- Paid time off (PTO)
- Paid volunteer time off
- Fully remote work with home office stipend
- Parental bonding leave
- Clinical-grade whole genome sequencing for you and your family (private and confidential)
- Redefine how people understand themselves through their DNA
- Build category-defining products alongside scientists, engineers, and innovators
- Contribute to technology that will improve and extend millions of lives
- Shape one of the most important emerging categories in AI and healthcare
Sequencing Inc. is an equal opportunity employer. All aspects of employment, including the decision to hire, promote, discipline, or discharge, will be based on merit, competence, performance, and business needs. We do not discriminate based on race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.
Sequencing Inc. may use artificial intelligence (AI) or automated tools as part of the recruiting and hiring process, including for application screening and candidate evaluation. These tools may analyze information provided in your application materials or during the hiring process. Where required by applicable law, candidates may request a reasonable accommodation or an alternative selection process by contacting [email protected].
Similar Jobs
Big Data • Food • Hardware • Machine Learning • Retail • Automation • Manufacturing
Lead shopper and category insights for Meijer, using syndicated, shopper, and retailer data to develop category strategies, planograms, and dashboards that drive assortment, promotion, and merchandising recommendations to grow sales and market share. Collaborate with sales, buyers, and cross-functional teams and support joint business planning and performance optimization.
Top Skills:
ApolloDunnhumbyIri/CircanaJdaExcelMicrosoft PowerpointNielseniqNumeratorPower BIPower QueryShelfiqSpectraTableauVendornet
.png)
eCommerce • Fintech • Hardware • Payments • Software • Financial Services
Outbound-focused senior account executive responsible for sourcing and closing new restaurant merchant logos. Duties include prospecting, discovery, demos, consultative selling of Square ecosystem, field relationship building, partnering with BD/Product/Marketing, managing the sales cycle and onboarding, and meeting monthly sales KPIs using Salesforce.
Top Skills:
SalesforceSquare
Cloud • Fintech • Software • Business Intelligence • Consulting • Financial Services
Lead and manage audit, review, and compilation engagements for construction clients. Oversee engagement planning, staffing, budgeting, fieldwork, risk assessment, and reporting. Advise on complex GAAP and FASB issues, support clients with accounting compliance and ASC updates, provide training, supervise teams, and participate in business development and community activities.
What you need to know about the Los Angeles Tech Scene
Los Angeles is a global leader in entertainment, so it’s no surprise that many of the biggest players in streaming, digital media and game development call the city home. But the city boasts plenty of non-entertainment innovation as well, with tech companies spanning verticals like AI, fintech, e-commerce and biotech. With major universities like Caltech, UCLA, USC and the nearby UC Irvine, the city has a steady supply of top-flight tech and engineering talent — not counting the graduates flocking to Los Angeles from across the world to enjoy its beaches, culture and year-round temperate climate.
Key Facts About Los Angeles Tech
- Number of Tech Workers: 375,800; 5.5% of overall workforce (2024 CompTIA survey)
- Major Tech Employers: Snap, Netflix, SpaceX, Disney, Google
- Key Industries: Artificial intelligence, adtech, media, software, game development
- Funding Landscape: $11.6 billion in venture capital funding in 2024 (Pitchbook)
- Notable Investors: Strong Ventures, Fifth Wall, Upfront Ventures, Mucker Capital, Kittyhawk Ventures
- Research Centers and Universities: California Institute of Technology, UCLA, University of Southern California, UC Irvine, Pepperdine, California Institute for Immunology and Immunotherapy, Center for Quantum Science and Engineering
