St. Jude Children's Research Hospital - ALSAC
Principal Data Scientist, Marketing Analytics and Data Science (Hybrid)
Be an Early Applicant
Lead the development of Marketing Mix Modeling capabilities, collaborating with teams to align insights with business objectives, mentor junior data scientists, and drive innovation in donor intelligence.
At ALSAC you do more than make a living; you make a difference.Job DescriptionALSAC is seeking a visionary Principal Data Scientist to lead the development and evolution of our Marketing Mix Modeling (MMM) capabilities within a newly formed Marketing Analytics and Data Science team. This net-new role offers a unique opportunity to shape enterprise-wide measurement frameworks, drive strategic planning through scenario simulation, and pioneer AI-driven innovation in donor intelligence.As a senior individual contributor, you will provide technical leadership, collaborate with external vendors in a build-operate-transfer model, and mentor junior data scientists. You’ll translate complex business questions into actionable analytical frameworks, ensuring modeling outputs are both rigorous and aligned with strategic goals.Key Responsibilities1. MMM Capability Ownership
Lead the design, validation, and continuous improvement of MMM solutions. Collaborate with vendors and internal teams to ensure scalable, accurate, and business-aligned models.2. Cross-Functional Partnership
Work closely with marketing, finance, and media teams to align modeling efforts with business objectives and ensure insights are relevant and actionable.3. Model Quality & Innovation
Champion data integrity, model validation, and methodological innovation. Stay ahead of industry trends in MMM, MTA, and causal inference.4. Testing & Experimentation Strategy
Design robust testing frameworks to evaluate model reliability pre- and post-deployment.5. Integrated Measurement Strategy
Support integration of MMM with other measurement approaches (e.g., MTA) to enable a unified view of marketing performance.6. Analytical Framework Development
Translate complex business challenges into structured analytical approaches. Collaborate with analysts and stakeholders to ensure alignment with strategic goals.7. Mentorship & Best Practices
Mentor junior team members, promote modeling standards, and foster a culture of excellence and continuous learning.Top Skills & ExperienceI. Advanced Modeling & Causal Inference
We like people who are different…because we’re different, too. As one of the world’s most iconic and respected nonprofits, we know what it’s like to stand out. That’s why we’re looking at you. Your background, perspective, and desire to make an impact set you apart. As we work to help St. Jude cure childhood cancer, we're calling on the game-changers, innovators and visionaries to join our family. Not just for the kids of St. Jude, but also for you. Because at ALSAC, we develop and celebrate our employees. So, bring your whole, authentic self and become part of our shared mission: Finding cures. Saving children.®
Lead the design, validation, and continuous improvement of MMM solutions. Collaborate with vendors and internal teams to ensure scalable, accurate, and business-aligned models.2. Cross-Functional Partnership
Work closely with marketing, finance, and media teams to align modeling efforts with business objectives and ensure insights are relevant and actionable.3. Model Quality & Innovation
Champion data integrity, model validation, and methodological innovation. Stay ahead of industry trends in MMM, MTA, and causal inference.4. Testing & Experimentation Strategy
Design robust testing frameworks to evaluate model reliability pre- and post-deployment.5. Integrated Measurement Strategy
Support integration of MMM with other measurement approaches (e.g., MTA) to enable a unified view of marketing performance.6. Analytical Framework Development
Translate complex business challenges into structured analytical approaches. Collaborate with analysts and stakeholders to ensure alignment with strategic goals.7. Mentorship & Best Practices
Mentor junior team members, promote modeling standards, and foster a culture of excellence and continuous learning.Top Skills & ExperienceI. Advanced Modeling & Causal Inference
- Expertise in MTA, Bayesian modeling, Markov chains, SEM, and survival analysis.
- Skilled in causal inference techniques (DiD, synthetic control, BART).
- Ability to tailor models to varying data richness across channels.
- Experience building modular forecasting pipelines with elasticity-aware logic.
- Skilled in designing scenario simulators with constraints and real-time feedback.
- Familiarity with ensemble models, neural networks, and meta-modeling.
- Proven ability to translate complex outputs into executive-ready insights.
- Experience presenting to senior leadership and crafting strategic narratives.
- Skilled in communicating uncertainty and scenario governance.
- Deep understanding of feature engineering, temporal alignment, and data lineage.
- Experience collaborating with ML engineers and MLOps teams.
- Proficient in working with structured/unstructured data across CRM, media, finance, and APIs.
- Enterprise-Wide Modeling: Extend MMM frameworks to include donor experience, bequests, and internal investments.
- Scenario Simulation Leadership: Co-lead the design of ALSAC’s What-If Scenario Simulator for strategic planning.
- AI & GenAI Innovation: Contribute to AI agent and GenAI tool development for donor intelligence and scenario planning.
- Governance & Transparency: Implement model governance, version control, and explainability tools (e.g., SHAP, LIME).
- Strategic Growth Path: This role evolves with ALSAC’s analytics maturity, offering long-term leadership opportunities.
- Bachelor’s degree in Statistics, Economics, Computer Science, or related quantitative field required.
- 10+ years of experience in marketing analytics, data science, or econometric modeling, with a focus on MMM.
- Advanced degree (Master’s or PhD) strongly preferred.
- Demonstrated success in enterprise-scale modeling and strategic analytics leadership.
- Core Medical Coverage: (low cost low deductible Medical, Dental, and Vison Insurance plans)
- 401K Retirement Plan with 7% Employer Contribution
- Exceptional Paid Time Off
- Maternity / Paternity Leave
- Infertility Treatment Program
- Adoption Assistance
- Education Assistance
- Enterprise Learning and Development
- And more
ALSAC is an equal employment opportunity employer.
ALSAC does not discriminate against any individual with regard to race, color, religion, sex, national origin, age, sexual orientation, gender identity, transgender status, disability, veteran status, genetic information or other protected status.
No Search Firms:
ALSAC does not accept unsolicited assistance from search firms for employment opportunities. All resumes submitted by search firms to any ALSAC employee or ALSAC representative via email, the internet or in any form and/or method without being contacted and approved by our Employee Experience team and without a valid written search agreement in place will result in no fee being paid if a referred candidate is hired by ALSAC.
Top Skills
Bayesian Modeling
Causal Inference Techniques
Marketing Mix Modeling
Markov Chains
Structural Equation Modeling
Similar Jobs
Fintech • Financial Services
As a Personal Banker, you'll build customer relationships, provide banking services, and assist with account openings and credit applications, ensuring compliance with regulations.
Fintech • Financial Services
The Branch Operations Coordinator will manage operational tasks, support customer transactions, resolve issues, and enhance customer experience in a banking environment.
Fintech • Financial Services
Wells Fargo is seeking a Branch Operations Coordinator to support customer experience, perform operational tasks, and enhance team productivity. Responsibilities include processing transactions, assisting customers, and resolving operational issues.
What you need to know about the Los Angeles Tech Scene
Los Angeles is a global leader in entertainment, so it’s no surprise that many of the biggest players in streaming, digital media and game development call the city home. But the city boasts plenty of non-entertainment innovation as well, with tech companies spanning verticals like AI, fintech, e-commerce and biotech. With major universities like Caltech, UCLA, USC and the nearby UC Irvine, the city has a steady supply of top-flight tech and engineering talent — not counting the graduates flocking to Los Angeles from across the world to enjoy its beaches, culture and year-round temperate climate.
Key Facts About Los Angeles Tech
- Number of Tech Workers: 375,800; 5.5% of overall workforce (2024 CompTIA survey)
- Major Tech Employers: Snap, Netflix, SpaceX, Disney, Google
- Key Industries: Artificial intelligence, adtech, media, software, game development
- Funding Landscape: $11.6 billion in venture capital funding in 2024 (Pitchbook)
- Notable Investors: Strong Ventures, Fifth Wall, Upfront Ventures, Mucker Capital, Kittyhawk Ventures
- Research Centers and Universities: California Institute of Technology, UCLA, University of Southern California, UC Irvine, Pepperdine, California Institute for Immunology and Immunotherapy, Center for Quantum Science and Engineering
