Manager, Denials and Appeals

Natera is a global leader in cell-free DNA (cfDNA) testing, committed to transforming how we diagnose and manage genetic diseases. Our proprietary technology platform powers a range of testing applications across oncology, women’s health, and organ health. With a focus on innovation, scientific excellence, and personalized care, Natera aims to make personalized genetic testing and diagnostics accessible to everyone. Our team is driven by a mission to change the management of disease worldwide and improve outcomes for millions of patients.

The Manager, Denials and Appeals is responsible for leading and optimizing the denials management and appeals operations within the revenue cycle function. This role ensures the timely and accurate resolution of claim denials, drives root cause analysis, and develops strategies to minimize future denials. The Manager will lead a team of specialists and collaborate cross-functionally to maximize reimbursement and support Natera’s mission in delivering high-quality diagnostic services.

• Lead and supervise the day-to-day operations of the denials and appeals team, ensuring productivity and quality standards are met.

• Develop and implement best practices for denial prevention, management, and appeals submission.

• Collaborate with billing, eligibility, and insurance verification teams to streamline end-to-end revenue processes.

• Analyze denial trends, reimbursement issues, and payer behaviors; develop mitigation strategies and process improvements.

• Oversee training, coaching, and performance management of denial and appeals staff; foster a positive team culture.

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• Serve as a liaison with internal stakeholders to support revenue cycle initiatives and system enhancements.

• Ensure timely and accurate submission of appeals and resolution of denied claims in compliance with payer requirements.

• Maintain up-to-date knowledge of billing, coding, and compliance regulations, especially within a laboratory setting.

• Monitor team performance metrics and KPIs; report outcomes and implement corrective actions as needed.

• Audit processes for adherence to internal policies and regulatory guidelines; drive continuous improvement.

• Bachelor’s degree in healthcare administration, business, or a related field (or equivalent experience).

• Minimum 5 years of experience managing denials and appeals in a high-volume, fast-paced billing environment—laboratory setting preferred.

• Proven ability to lead and motivate large teams effectively.

• Strong knowledge of medical billing, coding, payer reimbursement policies, and compliance regulations.

• Excellent analytical, organizational, and communication skills.

• Experience with billing systems and proficiency in interpreting and managing data.

• Knowledge of HIPAA regulations and experience handling PHI in accordance with compliance standards.

• This position requires regular access to Protected Health Information (PHI) and compliance with all applicable privacy and security standards.

• Experience with revenue cycle technology platforms and EHR systems preferred.