Director, CMC Project Management

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers.  The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding scientists in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

Revolution Medicines is seeking a motivated individual who will be responsible for managing cross-functional CMC project management activities in support of Revolution Medicines’ pipeline compound development and clinical programs.   This role will have people management responsibilities along with team leadership responsibilities, reporting into the Sr. Director, CMC Project Management.

Responsibilities:

• Provide project management support to CMC teams for projects ranging from Pre-IND through different phases of clinical development and commercialization.

• Enable CMC leads and/ or functional leads in implementing comprehensive CMC strategies and development plans and driving the CMC timelines to meet project’s needs.

• Collaborate with CMC lead(s) to plan and facilitate regular and effective CMC project meetings with structured agendas and accurate meeting minutes; follow up on action items.

• Proactively identify potential key issues and communicate with key stakeholders and management in a timely manner.

• Participate in the CMC portfolio review process to support the growing pipeline and provide input to senior management

• Collaborate with CMC functional areas to ensure successful execution of CMC development strategy.

Required Skills, Experience and Education:

• B.S. or M.S. or Ph.D. degree in Pharmaceutics, Chemistry, Chemical engineering or closely related field.

• A minimum of 8 years CMC project management experience with small molecule development experience.

• Experience working with global project teams and external development partners a plus.

• Knowledge of current ICH guidelines, GMP guidelines, and related industry practices.

• Working experience and knowledge of regulatory submissions (IND, IMPD, NDA and MAA). Understanding of development phases, associated CMC deliverables, and interactions of various functional areas and how each relates to a comprehensive strategy.

• Demonstrated strong cross-functional team and strategic leadership skills with people management experience a plus.

• Demonstrated experience of working with complex development challenges with multidisciplinary teams to realize project objectives.

• A self-starter with ability to work independently, deal with ambiguity and to develop a CMC development strategy in collaboration with other functions.

• Ability to communicate effectively with team members with a diverse range of backgrounds.

• Ability to interpret complex project information and demonstrate agility in responding to changing project needs.

• Effective written and verbal communication skills and interpersonal skills

Preferred Skills:

• Small molecule development experience.

• Experience working with external teams and interfacing with development partners.

• People management experience.

The base salary range for this full-time position is $204,000 to $255,000 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact [email protected].

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