Jobs at Arrowhead Pharmaceuticals

Supports global regulatory projects for RNAi-based therapeutics, including preparation and submission of INDs, CTAs, marketing applications, briefing documents, and progress reports. Develops regulatory strategies, coordinates health authority interactions, manages submission plans and timelines, reviews technical documentation, monitors regulatory intelligence, and advises cross-functional development teams on compliance and risk mitigation.

Leads corporate FP&A, including annual planning, long-range planning, forecasting, executive and Board reporting, variance analysis, scenario modeling, and G&A finance partnering. Supports partnership finance, financial decision-making, and continuous improvement of FP&A systems and processes, including Anaplan. Collaborates with executive leadership, Accounting, IT, and business functions across the organization.

Prepares SEC filings, technical accounting analyses, monthly and quarterly close activities, reconciliations, disclosure checklists, audit materials, and SOX-compliant controls. Partners with Investor Relations, Legal, Treasury, Tax, IT, and auditors to ensure accurate and timely financial reporting. Supports accounting policy improvements, reporting calendars, variance analysis, and technical areas including leases, equity, debt, and EPS disclosures.

Join the biometrics team to develop SDTM and ADaM dataset checks, perform QC from raw data to ADaM of key endpoints, deliver ad-hoc analyses, collaborate with data management and statisticians, participate in study team activities, and help develop departmental standards, processes, and training.

The Director, Contracts & Pricing will develop and execute pricing strategies, optimize product access, monitor market dynamics, and collaborate cross-functionally to enhance brand value.

Design and maintain secure endpoint baselines using Intune/Group Policy, triage security alerts, deploy conditional access and MFA, manage EDR/firewall policies, automate with PowerShell, ensure compliance through audits and documentation, and coordinate with IT to reduce risk.

Lead brand strategy and launch execution for Plozasiran, building and managing a high-performing marketing team. Drive positioning, omnichannel campaigns, HCP and patient messaging, agency relationships, budgets, market insights, and cross-functional alignment with Medical Affairs, Market Access, and Sales to achieve launch objectives.

Manage clinical quality documents within the eQMS, coordinating development, review, approval, and retirement of SOPs, work instructions, templates, and forms. Ensure documents comply with GCP/ICH/GVP/GLP and regulatory expectations, drive cross-functional review workflows, maintain inspection readiness, produce document KPIs, support eQMS (Veeva) enhancements, and liaise between Clinical Development and QA to improve document processes and system functionality.

Lead pharmacometrics and clinical pharmacology strategies for Arrowhead's global clinical development, ensuring scientific rigor and regulatory alignment in trial designs and submissions.

Lead delivery and continuous improvement of Dynamics 365 Finance & Operations for Finance, Procurement, AP/AR, Fixed Assets, PMA, and Cost Management. Act as primary IT liaison to Finance, design solutions and integrations, govern vendors, ensure compliance (SOX, 21 CFR Part 11, CSA), support audits, and develop team members while driving roadmap, process improvements, and Power BI reporting.

Lead design and optimization of Arrowhead's end-to-end supply network, build advanced network and capacity models, drive S&OP inputs, implement KPIs and dashboards, lead cross-functional improvement initiatives, develop capital and financial business cases, and advise senior leadership on operational strategy and network resilience for clinical and commercial product supply.

Manage global tax compliance, ASC 740 tax provision and disclosures, corporate income and indirect tax filings, tax audits, third‑party advisors, SOX internal controls, and cross‑functional tax planning and documentation.

Lead global sourcing strategies for direct spend in a biotech supply chain. Oversee RFI/RFP, supplier selection, contract negotiation, supplier performance, risk mitigation, compliance (SOX, regulatory), and KPI-driven cost savings. Partner cross-functionally with Legal, Finance, CMC, and operations to implement procurement systems, supplier governance, and onboarding.

Lead technical strategy and execution for drug-device combination products from concept through commercialization. Own human factors/usability engineering, design controls, risk management, device characterization, design verification, regulatory submission content, vendor management, and cross-functional coordination for prefilled syringes, autoinjectors, and related delivery systems.

Lead statistical programming for clinical studies: review analysis plans and SDTM, develop ADaM databases, program analyses, perform ad-hoc/exploratory statistics, liaise with cross-functional teams, oversee CRO programming deliverables, and help implement departmental standards and training.

Support commercial launch and field sales for Redemplo and other portfolio products by translating commercial strategy into field targets, territory design, incentive compensation, CRM/data optimization, KPI reporting, vendor and fleet management, and budget tracking. Collaborate with Sales, Marketing, IT, and Analytics to enable field excellence and operational efficiency.

Lead execution and continuous improvement of commercial technology platforms, analytics, reporting, and AI-enabled solutions. Own ZAIDYN platform administration and MDM, support Veeva systems, develop Power BI dashboards, manage vendors and budgets, lead cross-functional projects, and enable technology readiness for launches and international expansion.

Lead enterprise-wide learning and development strategy for a biotech company, designing GxP-compliant training, managing LMS, partnering with Quality and regulatory teams, overseeing onboarding, technical and leadership programs, and ensuring audit-ready training records and metrics.

Support GCP quality assurance activities including audit planning and execution, QMS (Veeva) management, SOP review, deviation/CAPA/SCAR management, risk plans, site metrics, and inspection support to ensure regulatory compliance and data integrity.

Lead strategic planning and operational excellence for Global Operations and Product Delivery. Own portfolio prioritization, governance, long-range planning, trade policy, risk and network strategy, supplier/partnership management, change management, budget/metrics, and cross-functional alignment to maximize asset value and organizational readiness.